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Forskningsprojekt: Exercise therapy in patients with osteoarthritis of the knee: effects of high dosage exercise and prediction of clinical outcomes The project is a ongoing Nordic project and includes a PhD-project
Wim Grooten, NVS KI Karin Harms-Ringdahl, NVS KI Annette Heijne, NVS KI Tom Arild Torstensen, NVS KI Håvard Østerås, Department of Neuromedicine and Movement Science NTNU
The aim is to evaluate the effect and prognostic factors of therapeutic exercise with a high vs. low dosage exercise therapy on pain, quality of life, mental and physical function, return to work, and health economics in patients with knee osteoarthritis. The project adopts a longitudinal RCT-design. In total, 200 patients with X-ray verified knee osteoarthritis will follow a scheduled high vs. low dose treatment protocol 3 times/week for 12 weeks. Self-perceived quality of life, pain, mental function, and objective measures of physical function will be measured at baseline, after treatment and at a six- to 12-month follow-up. A study protocol for this project was recently published in 2018, and the project is registered at ClinicalTrials. Innovation: to add knowledge on whether exercise dose can be related to short- and long-term treatment effects, and how it may be cost-effective. Partners: Collaboration between researchers in Sweden (KI) and Norway (Norwegian University of Science and Technology, NTNU) with data collection sites in Sweden as well as Norway.