View - Dalarna University

Project leader

Project Members

Mevludin Memedi
Jerker Westin
Peter Funk, Computer Science Mälardalens University
Taha Khan, Datateknik Högskolan Dalarna
Dag Nyholm, Neurology, Neuroscience Uppsala University

Project Period

01-01-2010 - 31-12-2012

Project Status

Completed

Description

Determining treatment outcome and follow-up of patients with fluctuations in motor performance, such as in advanced Parkinson´s disease is difficult in practice. In previous work by the research group, a test battery for assessing patient state in advanced Parkinson´s disease, consisting of self assessments and motor tests (tapping and spiral drawing) has been developed for a hand computer with touch screen in a telemedicine setting.

The research project E-MOTIONS is about developing, applying and evaluating IT-based methods for supporting treatment and evaluation of treatments for Parkinson´s disease with motor fluctuations. This includes further development of the test battery system and an analysis of its cost-benefit. Expected results are an increased ability to early find accurate individual treatment and less need to experiment with different dosages.

Keywords

Beslutsstödsystem, Parkinson, Levodopa, Duodopa, Motoriktest, Elektronisk dagbok, Webbgränssnitt, Utvärdering av behandling, Decision Support System, Parkinson, Levodopa, Duodopa, Motor test, Electronic diary, Web interface, Treatment assessment

Research Profile

Complex Systems - Microdata Analysis

Subject

Computer Engineering

Financiers

Abbott Product Operations AG
KK-stiftelsen
Nordforce Technology AB

Publications

Dougherty, Mark, Westin, Jerker. Slutrapport för projektet E-MOTIONS, 2013. Report.
Khan, Taha, Westin, Jerker, Dougherty, Mark. Motion cue analysis for parkinsonian gait recognition, Open Biomedical Engineering Journal, 2013, Vol. 7, 1-8. Article : refereed.
Memedi, Mevludin, Westin, Jerker, Nyholm, Dag. Spiral drawing during self-rated dyskinesia is more impaired than during self-rated off, Parkinsonism & Related Disorders, 2013, Vol. 19, No. 5, 553-556. Article : refereed.
Khan, Taha, Westin, Jerker, Funk, Peter, Dougherty, Mark. Quantification of speech impairment in Parkinson's disease, Movement Disorders, 2012, Vol. 27, S510-S511. Article : refereed.
Westin, Jerker, Schiavella, Mauro, Memedi, Mevludin, Nyholm, Dag, Dougherty, Mark, Antonini, Angelo. Validation of a home environment test battery for supporting assessments in advanced Parkinson's disease, Neurological Sciences, 2012, Vol. 3, No. 4, 831-838. Article : refereed.
Westin, Jerker, Stenberg, Georg. Development of a test for spatial working memory in Parkinson's disease : sensitivity to medication induced periodic performance changes, European Journal of Neurology, 2012, Vol. 19, No. s1, 551-551. Article : refereed.
Khan, Taha, Westin, Jerker. Motion Cues Analysis for Parkinson Gait Recognition, 15th International Congress of Parkinson's Disease and Movement Disorders : 2011. Conference paper : refereed.
Khan, Taha, Westin, Jerker. Assessment of PD Speech Anomalies @ Home, 15th International Congress of Parkinson's Disease and Movement Disorders : 2011. Conference paper : refereed.
Khan, Taha, Westin, Jerker. Methods for Detection of Speech Impairment Using Mobile Devices, Recent Patents on Signal Processing, 2011, Vol. 1, No. 2. Article : refereed.
Memedi, Mevludin, Westin, Jerker, Nyholm, Dag, Dougherty, Mark, Groth, Torgny. A web application for follow-up of results from a mobile device test battery for Parkinson's disease patients, Computer Methods and Programs in Biomedicine, 2011, Vol. 104, No. 2, 219-226. Article : refereed.
Memedi, Mevludin, Westin, Jerker. Spiral drawing during self-rated dyskinesia is more impaired than during self-rated off, 15th International Congress of Parkinson's Disease and Movement Disorders : 2011. Conference paper : refereed.
Memedi, Mevludin, Westin, Jerker. Methods for detection of handwriting/drawing impairment using inputs from touch screens, Recent Patents on Signal Processing, 2011, Vol. 1, No. 2. Article : refereed.
Memedi, Mevludin. Mobile systems for monitoring Parkinson's disease, Örebro universitet, 2011. Licentiate thesis.
Westin, Jerker, Nyholm, Dag, Pålhagen, Sven, Willows, Thomas, Groth, Torgny, Dougherty, Mark, Karlsson, Mats. A pharmacokinetic-pharmacodynamic model for duodenal levodopa infusion, Clinical neuropharmacology, 2011, Vol. 32, No. 2, 61-65. Article : refereed.
Westin, Jerker, Dougherty, Mark, Nyholm, Dag, Groth, Torgny. A home environment test battery for status assessment in patients with advanced Parkinson's disease, Computer Methods and Programs in Biomedicine, 2010, Vol. 98, No. 1, 27-35. Article : refereed.
Westin, Jerker, Ghiamati Yazdi, Samira, Memedi, Mevludin, Nyholm, Dag, Johansson, Anders, Dougherty, Mark, Groth, Torgny. A new computer method for assessing drawing impairment in Parkinson's disease, Journal of Neuroscience Methods, 2010, Vol. 190, No. 1, 143-148. Article : refereed.
Westin, Jerker, Nyholm, Dag, Johansson, Anders, Memedi, Mevludin, Dougherty, Mark, Groth, Torgny, Pålhagen, Sven. 12-month results from a novel test battery used in a duodenal levodopa infusion trial, European Journal of Neurology, 2010, Vol. 17, No. s3, 21-21. Article : refereed.
Westin, Jerker. Decision support for treatment of patients with advanced Parkinson’s disease, Acta Universitatis Upsaliensis, 2010. Doctoral thesis.

Research Project: E-MOTIONS, Decision support in treatment of Parkinson's disease